Friday, February 24, 2012

During a process called bone resorption ...

What is osteoporosis? Bone is living tissue that is constantly being destroyed and rebuilt. When the balance between breakdown and restoration of disturbed - for example, hormonal changes or changes in diet - lose some bone minerals that contribute to its density and strength. Condition decrease bone density is called osteopenia. In a large loss of bone density occurs so that the bones are significantly weakened and prone to failure, a condition called osteoporosis (porous bone). Osteoporosis increases the risk of fractures, especially in the hips, spine and wrist. Although it can affect anyone, the risk of osteoporosis increases with age, affects women more often than men and is most common in Caucasian and Asian women. According to the National Osteoporosis Foundation (Nof), 10 million people in the U.S. have osteoporosis and another 34 million people have reduced bone mass and risk of the disease. Of those who have osteoporosis, 80% are women. Most people at risk of osteoporosis, without realizing it. It's called the "silent disease" because usually asymptomatic until a person has broken bones. This gap, often in the hip, vertebrae in the spine or wrist can happen with very little pressure and can lead to significant face pain and prolonged or permanent disability. If the fracture causes severe weakness and affects the overall health of the patient, it may be a factor in the death of the patient. Bones, above all, the combination of type I collagen protein and calcium phosphate. Protein forms a sponge network that is "mineralized" by adding a compound of calcium to bones and strong and flexible. Bone tissue that slowly but surely replaced. During a process called resorption bone cells called osteoclasts dissolve bone on a microscopic level and enzymes destroy the collagen network. This is accompanied by the formation of new bone cells called osteoblasts, which secrete osteokaltsynu and precursors of collagen and create a new structure of the protein. Frames, then create new mineralized bone. This continuous process is called bone turnover or bone remodeling and it occurs throughout the body, usually replacing approximately 8-10% of bone of the body each year. In childhood, bone formation occurs faster than bone resorption and bone mass increases to a maximum of 30 years. After this peak, slow down bone formation and resorption begins to outpace him, leading to a decrease in bone mass with age. Inadequate intake of calcium and vitamin D in infancy, the use of drugs that contain steroids (eg asthma medication), anorexia, activity, smoking, excessive alcohol consumption can all increase the risk of osteoporosis later in life man. Some diseases such as Cushing's disease,,,, and vitamin D deficiency can also affect bone health. Those with a strong family history of osteoporosis may be at increased risk of developing it themselves. Menopausal and postmenopausal women may experience increased rate of loss of bone mass with a decrease in. Passing >> << early may contribute to loss. In Nof, some women can lose up to 20% of bone mass in the first 5 to 7 years after menopause. Men with low >> << are also at risk for increased bone loss. Primary osteoporosis or age. This refers to osteoporosis develops without apparent reason. Much more common in women, but also can be seen in men, especially in older men. As mentioned earlier, some women's rate of bone loss is very high immediately after menopause, and fractures can occur in a relatively early age, but most women do not cause osteoporosis fractures while they are in the 60's or 70's. Lifestyle changes, calcium or vitamin D supplements and other medications that reduce bone loss can slow the progression of this type of osteoporosis. The lasix 40 meq secondary osteoporosis. This refers to bone loss because of other diseases. It affects both men and women may be associated with various disorders, including rheumatoid arthritis, hyperparathyroidism, Cushing's disease, chronic kidney disease, or medications such as anti-epileptics, glucocorticoids, or lithium. Treatment of underlying disease or problem may slow the loss of bone density secondary osteoporosis. .


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